diff --git a/Misc/NEWS.d/next/Core_and_Builtins/2026-10-22-14-45-00.gh-issue-160245.mEmO24.rst b/Misc/NEWS.d/next/Core_and_Builtins/2026-10-22-14-45-00.gh-issue-160245.mEmO24.rst
new file mode 100644
index 00000000000000..f62d937f556caa
--- /dev/null
+++ b/Misc/NEWS.d/next/Core_and_Builtins/2026-10-22-14-45-00.gh-issue-160245.mEmO24.rst
@@ -0,0 +1,2 @@
+Reduce the size of parser memo entries on 64-bit platforms by reordering
+fields to remove padding. Patch by Shamil Abdulaev.
diff --git a/Parser/pegen.h b/Parser/pegen.h
index 44f99310132839..95ad2c9b7c0a84 100644
--- a/Parser/pegen.h
+++ b/Parser/pegen.h
@@ -31,8 +31,8 @@
 
 typedef struct _memo {
     int type;
-    void *node;
     int mark;
+    void *node;
     struct _memo *next;
 } Memo;